Virtual drug screening leads to new compounds to treat pain and depression

Shoichet’s “docking” approach continues to produce better drugs with fewer side effects.

QBI continues research efforts to stave off future surges of COVID-19

Research into SARS-CoV-2 variants and potential therapies pushes forward

Arkin named next chair of Department of Pharmaceutical Chemistry

Arkin’s appointment to bolster collaborations between academia and industry for drug discovery.

Jamming the gears of a deadly virus

Team efforts at the School and beyond produce two potential treatments for COVID-19.

How targeting a key SARS-CoV-2 enzyme could lead to an antiviral drug

The chemical fragments could bind to and disable an enzyme that helps the virus replicate.

VR drug discovery makes precision therapy a reality

ChimeraX, virtual reality software developed at the UCSF Resource for Biocomputing, Visualization and Informatics, is now the tool of choice for computational structural biologists in the School of Pharmacy. The Jacobson Lab recently used ChimeraX to find a promising new cure for a drug-resistant...

Training computers to think more like scientists

Michael Keiser, PhD, and Kangway Chuang, PhD, want to use machine learning to speed the pace of drug discovery. By digging into the work of another lab, the pair realized how machine learning could lead scientists astray—and came up with methods to avoid its worst pitfalls.

Creating an inexhaustible database for drug molecules

School of Pharmacy researchers helped a free public database of potential drug molecules grow 100-fold.

Fraser appointed to Bowes Biomedical Investigator Program

Fraser developed several new tools for creating maps of macromolecules, a critical first step for finding new drugs.

Keiser receives $2.5 million to apply machine learning towards new therapies for Alzheimer’s, Parkinson’s

Michael Keiser, PhD, received a Ben Barres Early Career Acceleration Award from the Chan Zuckerberg Initiative, which will fund his research into novel therapies for neurodegeneration.

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