UCSF

Publications

  1. Bruning JM, Wang Y, Oltrabella F, Tian B, Kholodar SA, Liu H, Bhattacharya P, Guo S, Holton JM, Fletterick RJ, Jacobson MP, England PM. Covalent Modification and Regulation of the Nuclear Receptor Nurr1 by a Dopamine Metabolite. Cell Chem Biol. 2019 May 16; 26(5):674-685.e6. PMID: 30853418.

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  2. de Jesus Cortez F, Nguyen P, Truillet C, Tian B, Kuchenbecker KM, Evans MJ, Webb P, Jacobson MP, Fletterick RJ, England PM. Development of 5N-Bicalutamide, a High-Affinity Reversible Covalent Antiandrogen. ACS Chem Biol. 2017 12 15; 12(12):2934-2939. PMID: 28981251.

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  3. de Jesus Cortez F, Suzawa M, Irvy S, Bruning JM, Sablin E, Jacobson MP, Fletterick RJ, Ingraham HA, England PM. Disulfide-Trapping Identifies a New, Effective Chemical Probe for Activating the Nuclear Receptor Human LRH-1 (NR5A2). PLoS One. 2016; 11(7):e0159316. PMID: 27467220; PMCID: PMC4965143.

    View in: PubMed, PubMed Central

  4. England PM. Developing a photoreactive antagonist. Methods Mol Biol. 2013; 995:121-9. PMID: 23494376.

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  5. Aungst S, England PM, Thompson SM. Critical role of trkB receptors in reactive axonal sprouting and hyperexcitability after axonal injury. J Neurophysiol. 2013 Feb; 109(3):813-24. PMID: 23155176; PMCID: PMC3567381.

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  6. Harvey JH, Long DH, England PM, Whistler JL. Tuned-Affinity Bivalent Ligands for the Characterization of Opioid Receptor Heteromers. ACS Med Chem Lett. 2012 Aug 09; 3(8):640-644. PMID: 23585918.

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  7. England PM. Bridging the gaps between synapses, circuits, and behavior. Chem Biol. 2010 Jun 25; 17(6):607-15. PMID: 20609410.

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  8. Fleming JJ, England PM. AMPA receptors and synaptic plasticity: a chemist's perspective. Nat Chem Biol. 2010 Feb; 6(2):89-97. PMID: 20081822.

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  9. Fleming JJ, England PM. Developing a complete pharmacology for AMPA receptors: a perspective on subtype-selective ligands. Bioorg Med Chem. 2010 Feb 15; 18(4):1381-7. PMID: 20096591.

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  10. Wang X, Ratnam J, Zou B, England PM, Basbaum AI. TrkB signaling is required for both the induction and maintenance of tissue and nerve injury-induced persistent pain. J Neurosci. 2009 Apr 29; 29(17):5508-15. PMID: 19403818; PMCID: PMC2720992.

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  11. Cruz LA, Estébanez-Perpiñá E, Pfaff S, Borngraeber S, Bao N, Blethrow J, Fletterick RJ, England PM. 6-Azido-7-nitro-1,4-dihydroquinoxaline-2,3-dione (ANQX) forms an irreversible bond to the active site of the GluR2 AMPA receptor. J Med Chem. 2008 Sep 25; 51(18):5856-60. PMID: 18754610; PMCID: PMC2945402.

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  12. Argilli E, Sibley DR, Malenka RC, England PM, Bonci A. Mechanism and time course of cocaine-induced long-term potentiation in the ventral tegmental area. J Neurosci. 2008 Sep 10; 28(37):9092-100. PMID: 18784289; PMCID: PMC2586328.

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  13. Kaneko M, Hanover JL, England PM, Stryker MP. TrkB kinase is required for recovery, but not loss, of cortical responses following monocular deprivation. Nat Neurosci. 2008 Apr; 11(4):497-504. PMID: 18311133; PMCID: PMC2413329.

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  14. Nilsen A, England PM. A subtype-selective, use-dependent inhibitor of native AMPA receptors. J Am Chem Soc. 2007 Apr 25; 129(16):4902-3. PMID: 17391037. Note: This publication was highlighted in C&E News, 2007, April 12. Wasp Toxin Analog Expected to Clarify Role of Neuronal Receptors.

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  15. England PM. Rapid photoinactivation of native AMPA receptors on live cells using ANQX. Sci STKE. 2006 Apr 18; 2006(331):pl1. PMID: 16622183.

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  16. Adesnik H, Nicoll RA, England PM. Photoinactivation of native AMPA receptors reveals their real-time trafficking. Neuron. 2005 Dec 22; 48(6):977-85. PMID: 16364901. Note: This article was featured on the cover of Neuron.

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  17. Chen X, Ye H, Kuruvilla R, Ramanan N, Scangos KW, Zhang C, Johnson NM, England PM, Shokat KM, Ginty DD. A chemical-genetic approach to studying neurotrophin signaling. Neuron. 2005 Apr 07; 46(1):13-21. PMID: 15820690.

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  18. Chambers JJ, Gouda H, Young DM, Kuntz ID, England PM. Photochemically knocking out glutamate receptors in vivo. J Am Chem Soc. 2004 Nov 03; 126(43):13886-7. PMID: 15506725.

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  19. England PM. Unnatural amino acid mutagenesis: a precise tool for probing protein structure and function. Biochemistry. 2004 Sep 21; 43(37):11623-9. PMID: 15362846.

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