Research interests

Principal investigator


Michelle Arkin, PhD

Thomas William and Frederick John MacWilliam Distinguished Professor

Codirector, Small Molecule Discovery Center (SMDC)

Professor and Chair, Department of Pharmaceutical Chemistry

[email protected]


chemical biology, protein-protein interactions, screening, cancer, neurodegenerative disease, neglected diseases

Postdoctoral scholars

Andrew Ambrose, PhD
Postdoctoral Scholar
[email protected]

drug discovery, molecular biology, HTS assay development, neurodegenerative disease, chemical biology

Ziwen Jiang, PhD
Postdoctoral Scholar
[email protected]

chemical biology, protein-protein interactions

Markella Konstantinidou, PhD
Postdoctoral Scholar

medicinal chemistry, synthetic chemistry, multicomponent reactions, drug design

Yu-Hsuan Kuo, PhD
Postdoctoral Scholar
[email protected]

chemical biology, proteomics, protein-protein interactions

Graduate students

Chad Altobelli
CCB Graduate Student
[email protected]

genetic disorders, protein-protein interactions, structural biology, medicinal chemistry
Robert Amongre
PSPG Graduate Student 
drug discovery, Neurodegenerative disease, Chemical and molecular biology

Marcus Chin, MPhil
PSPG Graduate Student
[email protected]

high-throughput drug screening, Alzheimer’s disease, tau pathology

Dyana Kenanova
CCB Graduate Student
[email protected]edu
protein-protein interactions, high throughput screening, metabolic disease, medicinal chemistry, and chemical biology
Holly Vickery
CCB Graduate Student
[email protected]
chemical biology, high-throughput screening, cancer biology, protein-protein interactions
Johanna Virta 
CCB Graduate Student 
Protein-protein interactions, protein degradation, chemical biology, molecular biology

Senior scientists

prasanna kandel
Prasanna Kandel, PhD
Preclinical drug discovery, high-throughput drug screening, fragment-based ligand discovery, protein-small molecule biophysics, biochemical and cell-based assays, medicinal chemistry, molecular and cellular biology, chemical biology, epigenetics, neurodegenerative disease, cancer

Greg Lee, PhD
Specialist, Biophysics
[email protected]

structural biology, protein NMR, protein biophysics, protein dynamics, protein-protein and protein-ligand interactions

Jeff Neitz, PhD
Associate Adjunct Professor, Chemistry
[email protected]

synthetic chemistry, medicinal chemistry, neurodegenerative disease, cancer

Amanda P
Amanda Paulson, PhD
Specialist, Informatics
computational biology, database management, drug-induced liver injury, early-stage drug discovery

Grace Pohan, MS
Assistant Specialist
[email protected]

high-throughput screening, cell-based assay development, drug liver-induced injury, early stage drug discovery
Jezrael Lafuente Revalde, PhD
high-throughput screening, cell-based assay development, drug liver-induced injury, early stage drug discovery


Ninwe Maraha, PhD
Laboratory Manager
[email protected]



Kazuko Olson
Administrative Officer
[email protected]


Former team members




May H. Abdelaziz, PhD

Postdoctoral Scholar

Assistant Professor, University of Texas at Tyler, Tyler, TX

Kenny Ang, PhD Specialist  
Ambika Bhagi-Damodaran, PhD Postdoctoral Scholar Assistant Professor, Chemistry, University of Minnesota
Yuliya Birman Graduate Student Research Associate, Biodesy

Stacie Bulfer, PhD

Postdoctoral Scholar

Senior Scientist, Deciphera Pharmaceuticals, Lawrence, KS

Paul Burroughs Staff Research Associate Graduate Student, UCSF 
Sheng Chen, PhD Postdoctoral Scholar  
Steven Chen Specialist GE
Julia Davies Senior Scientist  
Shubhankar Dutta, PhD Postdoctoral Scholar  

Jether Amos Espinosa

Junior Specialist

Graduate Student, Yale University 

Yao Fan, PhD


Senior Scientist, Boehringer Ingelheim

Ken Hallenbeck Graduate Student Senior Scientific Researcher, Genentech

Frantz Jean-Francois, PhD

Postdoctoral Scholar

Scientist II, Frederick National Laboratory for Cancer Research, Frederick, MD

Auke Koops Graduate Student Intern  
Sarine Markossian, PhD Specialist  
Daniel Medina-Cleghorn, PhD Postdoctoral Scholar Scientist, Nurix Therapeutics

Connie Merron


Informatics Specialist, Recombinant Antibody Network, UCSF

Maxime van den Oetelaar Visitor Graduate  
Sam Pfaff, PhD Postdoctoral Scholar Scientist, Prolynx
Annet Saris Graduate Student Intern  
Takeshi Shida, PhD Postdoctoral Scholar  

Yinyan Tang, PhD


Scientist, Nektar Therapeutics, San Francisco, CA

Nupur Verma, PhD Postdoctoral Scholar  
Chris Wilson, PhD Associate Directory  
Mengqi Zhong, PhD Postdoctoral Scholar Scientist, REVOLUTION Medicines