People

Principal investigator

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Who

Research interests, hobbies

DeGrado

William DeGrado, PhD
Professor and Principal Investigator

[email protected]

UCSF profile

De novo protein design; membrane proteins; small molecule drug discovery for antimicrobials, influenza A virus, antifibrotics, and neurodegeneration; chemical biology; peptide design

Cycling, Music, Dance

Senior scientists

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Who

Research interests

Jo

Hyunil Jo, PhD
Assistant Adjunct Professor

[email protected]

Medicinal chemistry to fight against unconquered human diseases; chemical biology to understand the fundamental processes in life

Postdoctoral scholars

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Who

Research interests, hobbies

Matthew Chalkley, PhD
Postdoctoral Scholar

[email protected]

Design and characterization of de novo metalloproteins for better understanding of structure-function relationships in enzymatic reactions

Hyun Jun Yang, PhD
Postdoctoral Scholar

[email protected]

Molecular fingerprinting of prion strains in vivo and in vitro

Golf

Lam-Kiu Fong Eiranova, PhD
Postdoctoral Scholar

[email protected]

Structure and dynamics of membrane protein receptors, molecular dynamics simulations

hanging out with my family, riding bikes, riding public transportation to see where it goes, walking in new places, learning how to make new foods
Mann

Samuel Mann, PhD
Postdoctoral Scholar

[email protected]

Design and characterization of de novo proteins to bind non-biological, inorganic cofactors; development of structure-function relationships for artificial metalloenzyme catalysis

I really enjoy baking and, therefore, also enjoy exercising. It's all about balance.

Kehan Chen, PhD
Postdoctoral Scholar

[email protected]

De novo design and characterization of membrane proteins, especially transporters and channels

Mineralogy and linguistics

Lee Schnaider, PhD
Postdoctoral Scholar

[email protected]

Design and characterization of de novo proteins for biomedical applications

Redwood and mountain enthusiast. I love hiking, reading and live music.

Lei Lu, PhD
Postdoctoral Scholar

[email protected]

Study protein structures, PTMs and interactions using bioengineering, proteomics and design methods

Basketball, Soccer, Dota2

Ethel Tackie-Yarboi, PhD
Postdoctoral Scholar

[email protected]

Synthesis and functional characterization of AND-gated cancer therapeutics

reading, cooking, and spending time with family

Katie Hatstat
Postdoctoral Scholar

[email protected]

Design and characterization of transmembrane proteins and signaling mechanisms

running, soccer, making up recipes, and adventuring in the mountains with her dog

Yuda Chen
Postdoctoral Scholar

[email protected]

Protein design with chemical biology

Henry Pan
Postdoctoral Scholar

[email protected]

Amyloids, cryo-EM, fluorescence microscopy, and peptide design

Long-distance running, hiking, playing the piano, reading, indoor gardening

Kaipeng Hou
Postdoctoral Scholar

[email protected]

De novo metalloprotein design

Ian Bakanas
Postdoctoral Scholar

[email protected]

Design and characterization of de novo enzymes to catalyze new-to-nature transformations

Baking bread, watching basketball, and playing tennis poorly.

Graduate students

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Who

Research interests, hobbies

Sophia Tan
Biophysics (BP) program

sophia.t[email protected]

Automated de novo design of ligand-binding proteins using structural proteomics

board games, rock climbing

Hailey Wallace
Biophysics (BP) program

[email protected]

Design and characterization of de novo proteins for investigating the amyloid fibril formation pathway

Rian Kormos
Biophysics (BP) program

[email protected]

Development and validation of improved algorithms for de novo design of small molecule impermeable nanostructures

In my free time, I enjoy long walks around the city, backpacking, teaching myself the piano, and playing Dungeons & Dragons.

Leo Chen
Chemistry and Chemical Biology (CCB) program

[email protected]

Development of protease-activated tumor imaging agents and cancer therapeutics

Rose Yang
Chemistry and Chemical Biology (CCB) program

[email protected]

Design and characterization of de novo peptides for targeting tau polymorphs present in Alzheimer's disease

Outside of the lab, I enjoy reading, cooking, and going on runs through Golden Gate Park.

Stephanie Ouchida
Chemistry and Chemical Biology (CCB) program

[email protected]

Design of de novo small molecule binding proteins for drug delivery

I enjoy rock climbing, playing basketball, going to the gym, playing video games, all things BTS, and drinking boba!

David Larwood
Chemistry and Chemical Biology (CCB) program

[email protected]

Development of new strategies for antifungal therapeutics and drug delivery

I like SCUBA diving, gardening, singing, travel

Current interns, undergraduates and high school students

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Who

Research interests, hobbies

Junyi Xu
Undergraduate student
University of California, Berkeley

[email protected]

Protein design

Jiage Song
Undergraduate student
University of California, Berkeley

[email protected]

Small molecule binding protein design

Listen to music and play Mahjong

Vee Xu
Biotechnology Intern
City College of San Francisco Biotechnology Program

[email protected]

Histidine kinase engineering
Live Action Role Playing (LARP) games
Fusion Cooking and Cuisine
Biking at Cruising Speed

Associated adjunct faculty

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Who

Research interests

Yibing Wu, PhD
Assistant Adjunct Professor

[email protected]

Structure and dynamics of proteins using multidimensional NMR spectroscopy
protein modelling and drug docking
deep learning-based protein design and drug discovery

Administrative staffs

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WHO

What I do, hobbies

Clare Demer
Administrative Assistant

[email protected]

Support administrative, organizational, and scheduling needs for the lab

Singing, film photography