People
Principal investigator
|
Photo |
Who |
Research interests |
|---|---|---|
 |
William DeGrado, PhD |
De novo protein design; membrane proteins; small molecule drug discovery for antimicrobials, influenza A virus, antifibrotics, and neurodegeneration; chemical biology; peptide design |
Senior scientists
|
Photo |
Who |
Research interests |
|---|---|---|
 |
Hyunil Jo, PhD |
Medicinal chemistry to fight against unconquered human diseases; chemical biology to understand the fundamental processes in life |
 |
Yibing Wu, PhD |
Structure and dynamics of proteins using multidimensional NMR spectroscopy; protein modelling and drug docking. |
Postdoctoral scholars
|
Photo |
Who |
Research interests |
|---|---|---|
 |
Ketaki Belsare, PhD |
Design, characterization and evolution of de novo proteins for small molecule biocatalysis |
 |
Matthew Chalkley, PhD |
Design and characterization of de novo metalloproteins for better understanding of structure-function relationships in enzymatic reactions. |
 |
Hyun Jun Yang, PhD |
Molecular fingerprinting of prion strains in vivo and in vitro |
 |
Huong Tran Kratochvil, PhD |
Influenza A and B matrix protein structure and mechanism |
 |
Lam-Kiu Fong Eiranova, PhD |
Structure and dynamics of membrane protein receptors, molecular dynamics simulations |
 |
Samuel Mann, PhD |
Design and characterization of de novo proteins to bind non-biological, inorganic cofactors; development of structure-function relationships for artificial metalloenzyme catalysis |
 |
Greg Merz, PhD |
Structure of amyloid filaments involved in neurodegeration, cryo-electron microscopy |
 |
Robert Newberry, PhD |
Exploring molecular determinants of protein folding, misfolding, and amyloid formation through chemical biology and biophysics |
 |
Nicholas Polizzi, PhD |
Design and characterization of de novo proteins that selectively bind small molecules |
 |
Lee Schnaider, PhD |
Design and characterization of de novo proteins for biomedical applications |
 |
Sam Schneider, PhD |
Design and characterization of de novo proteins for enzymatic catalysis |
 |
Lei Lu, PhD |
Study protein structures, PTMs and interactions using bioengineering, proteomics and design methods. |
 |
Nina Hentzen, PhD |
Design and characterization of de novo proteins that bind polypeptide chains |
Graduate students
|
Photo |
Who |
Research interests |
|---|---|---|
 |
Alison Maxwell |
Amyloid structure and neuropathological heterogeneity in Alzheimer’s disease |
 |
Bruk Mensa |
Structure and signal transduction mechanism of bacterial two component system histidine kinases; mechanism of action of antimicrobial peptide mimetics |
 |
Sophia Tan |
Automated de novo design of ligand-binding proteins using structural proteomics |
Administrative staff
|
PHOTO |
WHO |
What I do |
|---|---|---|
 |
Miranda Paulos |
Serve as point of contact for administrative inquiries; support administrative needs; coordinate visits from guest speakers; manage calendars |