People

Principal investigator

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Who

Research interests, hobbies

DeGrado

William DeGrado, PhD
Professor and Principal Investigator

[email protected]

UCSF profile

De novo protein design; membrane proteins; small molecule drug discovery for antimicrobials, influenza A virus, antifibrotics, and neurodegeneration; chemical biology; peptide design

Cycling, Music, Dance

Senior scientists

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Who

Research interests

Jo

Hyunil Jo, PhD
Assistant Adjunct Professor

[email protected]

Medicinal chemistry to fight against unconquered human diseases; chemical biology to understand the fundamental processes in life

Postdoctoral scholars

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Who

Research interests, hobbies

Hyunjun Yang, PhD
Postdoctoral Scholar

[email protected]

Molecular fingerprinting of prion strains in vivo and in vitro

Golf

Lam-Kiu Fong Eiranova, PhD
Postdoctoral Scholar

[email protected]

Structure and dynamics of membrane protein receptors, molecular dynamics simulations

hanging out with my family, riding bikes, riding public transportation to see where it goes, walking in new places, learning how to make new foods

Kehan Chen, PhD
Postdoctoral Scholar

[email protected]

De novo design and characterization of membrane proteins, especially transporters and channels

Mineralogy and linguistics

Lee Schnaider, PhD
Postdoctoral Scholar

[email protected]

Design and characterization of de novo proteins for biomedical applications

Redwood and mountain enthusiast. I love hiking, reading and live music.

Lei Lu, PhD
Postdoctoral Scholar

[email protected]

Study protein structures, PTMs and interactions using bioengineering, proteomics and design methods

Basketball, Soccer, Dota2

Ethel Tackie-Yarboi, PhD
Postdoctoral Scholar

[email protected]

Synthesis and functional characterization of AND-gated cancer therapeutics

reading, cooking, and spending time with family

Katie Hatstat
Postdoctoral Scholar

[email protected]

Design and characterization of transmembrane proteins and signaling mechanisms

running, soccer, making up recipes, and adventuring in the mountains with her dog

Yuda Chen
Postdoctoral Scholar

[email protected]

Protein design with chemical biology

Henry Pan
Postdoctoral Scholar

[email protected]

Amyloids, cryo-EM, fluorescence microscopy, and peptide design

Running, sports leagues, playing the piano, and cooking plant-based cuisine

Kaipeng Hou
Postdoctoral Scholar

[email protected]

De novo metalloprotein design

Sophia Tan
Postdoctoral Scholar

[email protected]

Automated de novo design of ligand-binding proteins using structural proteomics
board games, rock climbing

Ian Bakanas
Postdoctoral Scholar

[email protected]

Design and characterization of de novo enzymes to catalyze new-to-nature transformations

Baking bread, watching basketball, and playing tennis poorly

Sagar Bhattacharya
Postdoctoral Scholar

[email protected]

De novo protein design for enzyme catalysis and drug delivery in vivo

Chess

Nam Hyeong Kim
Postdoctoral Scholar

[email protected]

Function-directed protein design for biomedical applications with a parametrized scaffold and protein structure prediction incorporating molecular dynamics
Drumming, watching football, and sitting in the park

Adam McConnell
Postdoctoral Scholar

[email protected]

De novo protein design towards pharmaceutical and biomedical applications
Watching stand-up comedy, drumming, reading scifi/fantasy novels, solving nonograms

Graduate students

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Who

Research interests, hobbies

Rian Kormos
Biophysics (BP) program

[email protected]

Development and validation of improved algorithms for de novo design of small molecule impermeable nanostructures

In my free time, I enjoy long walks around the city, backpacking, teaching myself the piano, and playing Dungeons & Dragons.

Leo Chen
Chemistry and Chemical Biology (CCB) program

[email protected]

Development of protease-activated tumor imaging agents and cancer therapeutics

Rose Yang
Chemistry and Chemical Biology (CCB) program

[email protected]

Design and characterization of de novo peptides for targeting tau polymorphs present in Alzheimer's disease

Outside of the lab, I enjoy reading, cooking, and going on runs through Golden Gate Park.

Stephanie Ouchida
Chemistry and Chemical Biology (CCB) program

[email protected]

Design of de novo small molecule binding proteins for drug delivery

I enjoy rock climbing, playing basketball, going to the gym, playing video games, all things BTS, and drinking boba!

David Larwood
Chemistry and Chemical Biology (CCB) program

[email protected]

Development of new strategies for antifungal therapeutics and drug delivery

I like SCUBA diving, gardening, singing, travel

Henry Scott
Biophysics (BP) program

[email protected]

Design and characterization of bioorthogonal intercellular signaling systems.
Outside of lab I enjoy surfing, reading, playing chess, and searching for frog-themed memes.

Angelika Arada
Biophysics (BP) program

[email protected]

Design and characterization of de novo proteins for small molecule binding
Outside of lab, I like going to concerts, trying new restaurants, and playing video games.

Nicholas Freitas
Biophysics (BP) program

[email protected]

Development of Physics-based computational methods for de novo enzyme design.
Camping, hiking, photography, and astronomy

Giovanni Aviles
Biophysics (BP) program

[email protected]

Design and characterization of artificial metalloenzymes

Outside of lab, I enjoy climbing, traveling, and learning languages

Current interns, undergraduates and high school students

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Who

Research interests, hobbies

Jiage Song
Undergraduate student
University of California, Berkeley

[email protected]

Small molecule binding protein design

Listen to music and play Mahjong

Associated adjunct faculty

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Who

Research interests

Yibing Wu, PhD
Assistant Adjunct Professor

[email protected]

Structure and dynamics of proteins using multidimensional NMR spectroscopy
protein modelling and drug docking
deep learning-based protein design and drug discovery

Administrative staffs

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WHO

What I do, hobbies

 

Marcus Cavness, PhD
Administrative Assistant

[email protected]

Support administrative, organizational, and scheduling needs for the lab