UCSF

People

Principal investigator

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Who

Research interests

Giacomini

Kathleen M. Giacomini, PhD

Professor and Principal Investigator

[email protected]

  • Understanding the roles of membrane transporters in drug absorption, disposition, targeting, and in clinical drug response.
  • Discovering natural variants in transporter genes in ethnically diverse human populations that associate with variation in drug response

Administration

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Who

 
 

Administrative Analyst

 

Senior researchers

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Who

Research interests

Yee

Sook Wah Yee, PhD

Assistant Adjunct Professor

[email protected]

  • Investigating the discovery of transporters as drug targets
  • Utilizing genomewide data to identify transporter endogenous role and drug pharmacological action
Srinivasan

Shylaja Srinivasan

Clinical Instructor

[email protected]

  • Clinical Instructor in Pediatric Endocrinology

Staff

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Who

Responsibilities

Lin

Lawrence Lin, PhD

Project Director

[email protected]

Postdocs

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Who

Research interests

Huy Ngo, PhD

Postdoctoral Scholar

[email protected]

  • Understanding the role of bile acid transporters in drug-induced liver injury (DILI)
Zou

Ling Zou, PhD

Postdoctoral Scholar

[email protected]

  • Understanding species difference in renal transporters to better predict dosing and prevent drug-induced nephrotoxicity in humans
  • Examining interactions of excipients with intestinal influx transporters which may affect drug bioavailability and bioequivalence

Mina Azimi, PhD

Postdoctoral Scholar

[email protected]

  • Proteomic analysis of transporters at the blood-brain barrier across development to better understand age-related differences in drug response

Graduate students

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Who

Research interests

Jessica Enogieru, PharmD, BCPS

Graduate Student, Pharmaceutical Sciences and Pharmacogenomics

[email protected]

  • Discovery, analysis, and functional characterization of genetic factors that influence anti-hyperglycemic drug response to metformin

Bianca Vora

Graduate Student

[email protected]

  • Characterization of clinically relevant drug vitamin interactions mediated by thiamine transporter SLC19A3
  • Investigating ontogenetic changes in transporters expressed on the blood brain barrier to better predict drug exposure in pediatric populations

Megan Koleske

Graduate Student

[email protected]

  • Functional genomic studies of SLC22A5 to inform new treatment modalities for carnitine transporter deficiency

Dina Buitrago Silva

Graduate Student

[email protected]

  • Characterization of the orphan transporters within the SLC22 Family and discovery of their clinical phenotype
 

Xujia Zhou

Graduate Student

[email protected]

  • Understanding how SLC transporters and drug-related enzymes change through evolution and how these changes contribute to diseases