UCSF

UCSF/Genentech Postdoctoral Fellowship in Regulatory Science

Overview

In the past decade, a plethora of new healthcare products have been developed, including innovative drugs and biologics, genome and cell-based therapies, mobile health products and implantable devices. Corresponding to the surge in these innovative products, there has been a scarcity of well-trained individuals to expertly develop and evaluate them for safe and effective use. Importantly, there is a new need for individuals who have computational training to apply their skills to the development of drugs, biologics, and medical diagnostics. The educational mission of UCSF in regulatory science is to train a new generation of scientists by providing opportunities to broaden their knowledge about tools, methods, and standards to support regulatory science and medical product development.

The UCSF/Genentech postdoctoral fellowship is an experiential program that will provide the most outstanding postdocs with unique immersion experiences in regulatory science research and drug development, with a particular emphasis on pharmacometrics and clinical pharmacology.

Training Components

Our objective is that the fellow should have a sufficient foundation and breadth in his/her training to engage in and serve as an ambassador for regulatory science research and education. The fellow will receive a monthly stipend commensurate with education level and experience. In general, fellows will spend the first year at UCSF and the second year at Genentech, though the fellowship may be extended for a total of three years. The anticipated start date of the first year fellowship at UCSF will be on or around September 1, 2021. The fellowship components are:

Research and Training at UCSF (1 year)

During the first year, the fellow is expected to spend at least 90% of his/her time on a scientific research project. The research project will either extend an existing project or will be an entirely new one-year project. Many of these projects are collaborative research projects with the FDA, so fellows may also gain experience working with FDA scientists or rotating at FDA. In addition to research, the fellow will take the UCSF-Stanford CERSI Immersion Course in in Drug Discovery, Drug Development, and Regulation. The fellow is also expected to actively participate in all UCSF-Stanford CERSI seminars, meetings and events.

Immersion Experience in Industry (1 year)

Following the completion of the academic portion, fellows will be placed at Genentech to complement and extend his/her training in regulatory science, drug development, clinical pharmacology, and pharmacometrics. The fellow will be assigned a Genentech mentor and work alongside scientists in the Department of Clinical Pharmacology at Genentech. The mentors will help the fellow design the research project. The fellow is required to attend the annual UCSF-Stanford CERSI Innovations in Regulatory Science Summit.

Statement of Completion and Employment

Fellows will receive a document certifying their participation in the UCSF/Genentech Postdoctoral Fellowship in Regulatory Science upon completion of all training components. Please note that this fellowship does not guarantee job placements upon completion.

Eligibility Criteria

Applicants must hold a doctoral degree (PhD in pharmaceutical sciences, chemical/biomedical engineering, applied mathematics, biomedical sciences or another related field, or hold a PharmD). Preferably, the candidate will have experience in mathematical modeling and simulation in pharmacology or biology (e.g. population PK/PD modeling, PBPK, quantitative systems pharmacology) or experience in transporter biology. The candidate must have an excellent record of academic achievement.

Application Process

Applicants are to submit items 1-6 of the required documents in the order listed below as a single PDF via email by August 1, 2021 to [email protected]. The PDF filename should follow this format: “LastName_UCSF/Genentech Fellowship Application.pdf”.

The following documents are required for a complete application:

  1. Application cover page containing: applicant’s full name, highest degree obtained (and date), degree granting institution, current institutional affiliation, email address, cell phone number, and complete mailing address.
  2. Statement of interest (1,000 word maximum) describing the applicant’s professional background and qualifications, regulatory science interests, skills to be acquired, and career goals, including how the fellowship would support those goals.
  3. Curriculum vitae (5 page maximum)
  4. Scientific publications or other writing samples (submit up to 2 publications). Applicant should indicate their role in the samples provided (i.e., primary drafter or other role). Publications are intended to gauge the research and writing capability of applicants and do not necessarily need to be on the topic of regulatory science.
  5. One letter of reference from the current research advisor to be submitted directly via email to [email protected] and must be received by the application deadline.
  6. Names of two additional references with complete contact information.

Selection Process

Applications will be reviewed by UCSF faculty and Genentech scientists.

 

The UCSF/Genentech postdoctoral fellowship in regulatory science is supported in part by Genentech, Inc.