UCSF

Publications

June 1, 2019

In Vitro Models for Thrombogenicity Testing of Blood-Recirculating Medical Devices

Expert Review of Medical Devices

Authors: Sarode DN, Roy S

 

February 17, 2019

Research Projects Supported by the University of California, San Francisco-Stanford Center of Excellence in Regulatory Science and Innovation

Clinical Pharmacology & Therapeutics, Volume 105, Number 4, pp. 815-818, April 2019

Authors: Kathleen M. Giacomini, Lawrence Lin, Russ B. Altman

 

January 20, 2019

Impact of Pharmaceutical Excipients on Oral Drug Absorption: A Focus on Intestinal Drug Transporters

Clinical Pharmacology & Therapeutics, Vol. 105, Number 2, pp. 323-325, February 2019

Authors: Ling Zou, Zhanglin Ni, Eleftheria Tsakalozou, Kathleen M. Giacomini

 

December 7, 2018

PathFX Provides Mechanistic Insights into Drug Efficacy and Safety for Regulatory Review and Therapeutic Development

PLOS Computational Biology, Vol. 14, Issue 12: e.1006614

Authors: Jennifer L. Wilson, Rebecca Racz, Tianyun Liu, Oluseyi Adeniyi, Jielin Sun, Anuradha Ramamoorthy, Michael Pacanowski, Russ Altman

 

September 27, 2018

Data mining of digitized health records in a resource-constrained setting reveals that timely immunophenotyping is associated with improved breast cancer outcomes

BMC Cancer, 2018 18:933

Authors: López-Pineda A, Rodríguez-Moran MF, Álvarez-Aguilar C, Fuentes Valle SM, Acosta-Rosales R, Bhatt AS, Sheth SN, Bustamante CD

 

August 6, 2018

Network Enhancement as a General Method to Denoise Weighted Biological Networks

Nature Communications 9, Article number: 3108 (2018)

Authors: Wang B, Pourshafeie A, Zitnik M, Zhu J, Bustamante CD, Batzoglou S, Leskovec J

 

August, 2018

Machine Learning in Chemoinformatics and Drug Discovery

Drug Dicovery Today, Volume 23, Issue 8, Pages 1538-1546, August 2018

Authors: Lo YC, Rensi SE, Torng W, Altman RB

 

February 2, 2018

Biomarkers: Delivering on the Expectation of Molecularly Driven, Quantitative Health

Experimental Biology Medicine, Vol. 243, Issue 3, pp. 313-322

Authors: Wilson JL, Altman RB

 

January 17, 2018

Chemical Reaction Vector Embeddings: Towards Predicting Drug Metabolism in the Human Gut Microbiome

Pacific Symposium of Biocomputing, Vol. 23, pp. 56-67

Authors: Mallory EK, Acharya A, Rensi SE, Turnbaugh PJ, Bright RA, Altman RB

 

March 21, 2017

Development of an Automated Assessment Tool for MedWatch Reports in the FDA Adverse Event Reporting System

Journal of the American Medical Informatics Association

Authors: Han L, Ball R, Pamer CA, Altman RB, Proestel S

 

March 21, 2017

Mechanical Performance of Cervical Intervertebral Body Fusion Devices: A Systematic Analysis of Data Submitted to the Food and Drug Administration

Journal of Biomechanics, Vol. 54, pp. 26-32

Authors: Peck JH, Sing DC, Nagaraja S, Peck DG, Lotz JC, Dmitriev AE

 

October 27, 2016

From the Patient's Point of View, How Should Minimally Invasive Glaucoma Surgeries be Evaluated?

American Journal of Ophthalmology, Vol. 172, pp. 12-14

Authors: Qui N. Cui, Kuldev Singh, George L. Spaeth

 

August 24, 2016

A Molecular Basis for Innovation in Drug Excipients

Clinical Pharmacology & Therapeutics, Vol. 101, Issue 3, pp. 320-323

Authors: John J. Irwin, Joshua Pottel, Ling Zou, Hong Wen, Susan Zuk, Xinyuan Zhang, Teague Sterling, Brian K., Shoichet, Robert Lionberger, Kathleen M. Giacomini

 

July 28, 2016

Identification and Quantitative Assessment of Uremic Solutes as Inhibitors of Renal Organic Anion Transporters, OAT1 and OAT3

Molecular Pharmaceutics, Vol. 12, Issue 9, pp. 3130-40

Authors: Chia-Hsiang Hsueh, Kenta Yoshida, Ping Zhao, Timothy W Meyer, Lei Zhang, Shiew-Mei Huang, Kathleen M Giacomini

 

April 20, 2016

A Research Roadmap for Next Generation Sequencing Informatics

Science Translational Medicine, Vol. 8, Issue 335, pp. 10

Authors: Altman RB, Prabhu S, Sidow A, Zook JM, Goldfeder R, Litwack D, Ashley E, Asimenos G, Bustamante DC, Donigan K, Giacomini KM, Johansen E, Khuri N, Lee E, Liang XS, Salit M, Serang O, Tezak Z, Wall DP, Mansfield E, Kass-Hout T

 

November 25, 2015

Unmet Needs: Research Helps Regulators do their Jobs

Science Translational Medicine, Vol. 7, Issue 315, pp. 22

Authors: Altman RB, Khuri N, Salit M, Giacomini KM

 

July 31, 2015

A Method for Systematic Discovery of Adverse Drug Events from Clinical Notes

Journal of the American Medical Informatics Association, Vol. 22, Issue 6, pp. 1196-204

Authors: Wang G, Jung K, Winnenberg R, Shah NIH