In light of COVID19 pandemic, we've devoted our protein and engineering expertise into understanding and developing therapy for SARS-CoV-2. Check out our publications and preprints:
Engineered ACE2 receptor traps potently neutralize SARS-CoV-2. Proceedings of the National Academy of Sciences, 202016093. https://doi.org/10.1073/pnas.2016093117
Bi-paratopic and multivalent VH domains block ACE2 binding and neutralize SARS-CoV-2. Nat Chem Biol. 2020 Oct 20. Epub ahead of print. PMID: 33082574. 10.1038/s41589-020-00679-1
Competitive SARS-CoV-2 Serology Reveals Most Antibodies Targeting the Spike Receptor-Binding Domain Compete for ACE2 Binding
MSphere, 5(5), 1–11.
Engineering luminescent biosensors for point-of-care SARS-CoV-2 antibody detection
MedRxiv, 2020.08.17.20176925. Under review
Trimeric SARS-CoV-2 Spike interacts with dimeric ACE2 with limited intra-Spike avidity
BioRxiv, 2020.05.21.109157. Under review

We are keenly focused on how cells remodel their extracellular proteome in health and disease. To understand and disrupt human disease-associated signaling processes, we develop enabling technologies with protein & antibody engineering and site-directed small molecule approaches.

lab team.

Recent news

Aug 30th, 2021 

Our annual Giants game outing! 

Jun 26th, 2021

Farewell to Jeff, Anum and Shion

Jun 10th, 2021

Congratulations Sophie Kong for passing the qualifying exam! 

Sophie Qulas
Dec 14th, 2019

Last Christmas Party of the decade!

christmas party

christmas party 2

christmas party 3
Nov 25th, 2019

Farewell to Duy Nguyen!

farewell party for Duy Nguyen
Nov 4th, 2019

Great dinner at CCB retreat with Wiita lab!

Sept 10, 2019 Go Giants at our annual game outing!
Giants game outing 2019

Aug 27, 2019

Farewell and best wishes to Professor Amy Weeks.


Jul 31, 2019

Welcome Julia Xu to the world!

triptych: mom with baby Julia, group 1, group 2

Jun 27, 2019


Thanks to the Quantitative Biosciences Institute (QBI) for their initiative to get to know each private investigator. Details: Interview with Jim Wells.

Jun 26, 2019

Congrats and thanks to Ninwe Maraha for our lab being awarded the LivingGreen certification from the Office of Sustainability. Details: School of Pharmacy leads in LivingGreen certifications.

Mar 17, 2019

Congrats to Cole Bracken for passing his qualifying exam.


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