Cell Encapsulation and Delivery

Cell encapsulation is a promising platform to overcome transplant graft rejection. Here, cells are surrounded with a semipermeable membrane, permitting the entry of nutrients and the release of therapeutic protein products, thus obtaining a sustained delivery of an active pharmaceutical molecule. The membrane serves to isolate the enclosed cells from the host immune system, preventing the recognition of the transplanted cells as foreign.  Such a cell encapsulation device would allow for transplantation of insulin-producing beta cells, helping to treat type 1 diabetes.

In collaboration with the Tang Lab.