UCSF

Intestinal Drug Transport Model

An Improved in vitro Intestinal Drug Transport Model 

(A) Sacrificial micromolding using photolithography allows for Caco-2 spheroid culture in geometrically controlled environments. (B) After 6 days, spheroids demonstrated lumenization and polarization representative of physiological intestinal epithelial cells.

Current/Future Work: Design and evaluate materials to treat autoimmune GI diseases

Recent Publications: Samy KE, Levy ES, et al. (2019) Scientific Reports

Point(s) of contact: Pierce Hadley