Bone drug delivery

Osteomyelitis is a bone or bone marrow infection that requires prolonged antibiotic therapy and surgical debridement. We are developing nanoparticles that both release a therapeutic payload and restructure damaged bone.


Acute osteomyelitis causes destruction of bone as seen in the jaw bone in the lower right of the image.


Osteoblasts attach themselves to a calcium phosphate microparticle capable of delivering an antibiotic payload to areas of bone infection.