Research laboratory of Rada Savic, PhD
Integrative Pharmacology Laboratory

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Who

Research interests

Principal investigator

Savic

Rada Savic, PhD

Principal Investigator

[email protected]

I work on methodological advancement and application of systems pharmacology models to drug development and therapy optimization problems in tuberculosis (TB), HIV, oncology, and diabetes.

Lab members

Strydom

Natasha Strydom, PhD

Postdoctoral Scholar

[email protected]

I am involved in modeling preclinical data with a current focus on emergence of antimycobacterial resistance. My work aims to integrate with translational models to predict improved treatment outcomes in patients with tuberculosis.

Priya Jayachandran, PharmD, MS

Clinical Pharmacology Fellow

[email protected]

I am employing computational modeling to investigate the pharmacokinetics and pharmacodynamics of tenofovir in healthy volunteers in order to predict target drug concentrations to prevent HIV. The findings from this pharmacometric analysis can be used to estimate the impact of non-adherence on HIV suppression.

Zhang

Nan Zhang, PhD

Academic Coordinator

[email protected]

I am creating a pharmacometric framework to evaluate clinical trial data on predictive biomarkers by identifying the different limitations of a typical Phase 2 study setting that could result in data analysis limitations through simulations using PK-biomarker-PD models.

Imperial

Marjorie Imperial

Graduate Student

[email protected]

I am developing computational models that investigate the variability observed in drug response. Ultimately, the goal is to apply these models to provide personalized medicine for improved diagnosis, therapies, and prognosis of diseases.

Emma Hughes

Graduate Student

[email protected]

I am using computational models to investigate the effects of variables such as malnutrition and HIV status on malaria chemoprevention and treatment strategies in children and pregnant women. Ultimately, our goal is to deliver an optimized dosing algorithm for children and women of all ages, weights, and nutritional statuses leading to cure and prevent malaria in every patient.

Katarina Vucicevic, PhD

Visiting Scholar

[email protected]

I am interested in modeling clinical data and exploring variability in drug pharmacokinetic profile, as well as response, and applying these models to an optimized dosing regimen. My current focus is HIV pre-exposure prophylaxis (PrEP).

William Fox

Research Data Analyst

[email protected]

Currently working with drug adherence patterns in patients and their effect on outcome. Additionally, aiding in applying analytic methods to high dimensional problems for feature extraction and model fitting.

Staff

Lu

Peter Lu

Administrative Analyst

[email protected]

 

 

Former lab members

Who

Formerly

Now

Ron Keizer, PhD

Postdoctoral Scholar and Research Scientist

CSO and co-founder at Insight-Rx, a startup focused on using pharmacometrics for precision dosing

Sirj Goswami, PhD

PhD student in Pharmaceutical Sciences and Pharmacogenomics

CEO and co-founder at Insight-Rx, a startup focused on using pharmacometrics for precision dosing

Jennifer Hibma, PharmD

Postdoctoral Scholar

Quantitative clinical pharmacologist at Pfizer

Yookhwan Noh, PhD

Postdoctoral Scholar

Assistant professor at Ulsan University Hospital

Sneha Gupta, PhD

Clinical Pharmacology Fellow

Clinical pharmacologist at Gilead Sciences, Inc.

Jodi Parikh, PhD

Visiting Scholar

Postdoc at Rutgers New Jersey Medical School

Allison Komirenko

Visiting Scholar

Biotech Clinical Research Fellow at Achaogen

Viktoria Grahnen, MSc Junior Specialist Labeling Strategist Manager at AbbVie
Malte Larsen, MSc Junior Specialist PhD Student at University of Copenhagen
John Fors, MS, NP-C Specialist Nurse Practitioner at Stanford Health Care
Desiree Legetth, MSc Junior Specialist Quality Assurance Officer at AstraZeneca
Niels Erik Olesen, PhD Junior Specialist Postdoc at Center for Research, University of Copenhagen
Ana Kalezic, MSc Junior Specialist PhD student at Uppsala University
Benjamin Guiastrennec, PharmD, MS Visiting Graduate Student

PhD Student at Uppsala University

Yusi Chen Visiting Graduate Student Graduate Student at Tsinghua University

Imke Bartelink, PhD

Clinical Pharmacology Fellow

Senior Pharmacometrician at MedImmune
Daniel Chan, PhD Postdoctoral Scholar  
Andrew Gewitz, PhD Postdoctoral Scholar

Clinical Pharmacologist at Regeneron

Stella Belonwu, BS