Mission and Overview

Map of WIHS sites

The ten WIHS study sites and the national data center.

Initially funded in 1993, the Women's Interagency HIV Study (WIHS) is the largest long-term observational study of the natural history of HIV in women in the United States. The WIHS is currently comprised of nine metropolitan consortia, including New York City (Bronx and Brooklyn), Washington, DC, San Francisco/Bay Area, Chicago, Atlanta, Miami, Alabama/Mississippi and North Carolina. The WIHS Data Management and Analysis Center (WDMAC) is located at Johns Hopkins University. Since the beginning, WIHS sites have enrolled a total of 4,868 participants who are HIV positive (70%) and a negative control group (30%). The WIHS is supported by the National Institute of Allergies and Infectious Diseases (NIAID) as well as the National Cancer Institute (NCI), the National Institute of Drug Abuse (NIDA), and the National Institute of Child Health and Human Development (NICHD).

All WIHS activities are governed by the Executive Committee, which consists of the WIHS site investigators and project directors who collectively set research priorities in collaboration with NIAID. The WIHS has various scientific working groups to provide guidance on the topics under study, including:

WIHS Working Groups